In the first world, Britain Granting an emergency permit for a coronavirus vaccine to Pfizer Wednesday. Hospitals in the country have already started emailing staff to schedule vaccinations, with the first doses being given in London at 7 am on Monday.

Pfizer plans to ship 800,000 doses to Britain in the coming days, with a total of 40 million orders. Each patient requires two doses, one month at a time.

Frontline hospital workers may be among the first to receive the vaccine, followed by workers and residents of nursing homes; People over 80 years old; And other health and social care workers.

One of the last hurdles faced by drug makers Children tested for the vaccine, Who have more active immune systems than adults and can have stronger interactions.

In an annual report on climate change and health published by The Lancet, collaborating authors from around the world say global warming has already occurred. It caused an increase of 50 percent In heat-related deaths in people older than 65, especially in Japan, China, India and parts of Europe.

In the United States, rising temperatures, along with pollution and wildfires, are endangering the health of Americans, with disastrous consequences for many elderly people. The authors have defended the case for a rapid transition to a green economy and called on lawmakers to act aggressively to limit the gases causing global warming in the next five years. “Climate action is a healthy recipe,” one of the authors told reporters.

In response to the The assassination of its chief nuclear scientistMohsen Fakhrizadeh, Iran on Wednesday issued a law ordering Instant intensification To enrich uranium to levels closer to weapons-grade fuel. The measure also requires the expulsion of international nuclear inspectors if US sanctions are not lifted by early February.

This week, officials in Iran sought to rewrite the murder as a science fiction episode, as competing intelligence agencies. Evade blame To the expiration of a fatal security. One report suggested that Israel executed Mr. Fakhrizadeh entirely by remote control, as they sprayed bullets from an automatic machine gun installed in a parked Nissan without a single killer being present at the scene.

Iranian officials He vowed to avenge his death Mr. Fakhrizadeh. A possible counterattack against Israel or the West Threatens to hinder efforts By the Biden administration coming to revive the nuclear deal with Iran.

Related: Israel moved Closer to another snap election, the fourth in two years, After Prime Minister Benjamin Netanyahu’s coalition partners joined the opposition in a preliminary vote to topple the unity government.

Since the year 1000, Ichiwa, above, has been a small cedar shop next to a shrine in Kyoto, Japan, serving grilled rice flour cakes – during wars, plagues, natural disasters, and the rise and fall of empires.

Now, while the coronavirus is ravaging a large portion of the global economy, the family that runs the store is among the few Business owners who are not anxious about their finances. Naomi Hasegawa, the owner, said one of the reasons for our “persistence” is “because we all hate the idea of ​​being the one to give it up.”

football: Despite frequent cases of inappropriate interaction with the young prospects, the French Football Federation allowed the man to do so Quietly transition from one job to anotherHe holds a certificate of high value issued by the federation that helped him to continue working in the sport.

Afghan peace talks: The Afghan government and the Taliban negotiators in Qatar agreed How to move forward with peace negotiations. The next phase of the talks will likely focus on a political roadmap and a long-term nationwide ceasefire.

Legalization of cannabis: A United Nations commission, with a highly anticipated decision, Vote to remove marijuana For medicinal use of a class of the most dangerous drugs in the world.

Hong Kong demonstrations: Pro-democracy activists Joshua Wong, Agnes Chau and Evan Lam They were sent to prison For their role in an anti-government rally last year.

Landing on the moon: China released video footage on Wednesday showing the arrival of the Chang’e-5 robotic spacecraft on the surface of the moon. you may Watch it here.

Lab meat: Singapore approved a lab-grown meat product from a US startupThis makes it the first in the world to receive government approval.

Glance: Above, kimchi was made at a market in Seoul, South Korea, in November. A dispute rages on social media between China and South Korea After a Chinese tabloid reported that China has set a world standard for pickled essential vegetables.

Live live: Valerie Giscard d’Estaing, the conservative former president of France who fought to change his country of politically polarized traditions for seven years, He died at 94 on Wednesday A complication from Covid-19.

What we read: Fox Newsletter “Merchandise”Twice a week, a comprehensive guide to what to buy and why to buy it. “I’ve read every single one of them,” says Taylor Lorenz, technology reporter at Styles. You especially like TikTok Tuesday releaseWritten by Rebecca Jennings, Vox Correspondent.

Watch: TikTok users have created a musical version From Disney’s animated movie “Ratatouille”, it displays in heavy increments of 60 seconds. Wellness!

Whether you’re looking for a project or just something to watch, At Home has our full suite of ideas About what to do while staying safe at home.

Benjamin Muller, a London-based reporter, explains why Britain’s quick approval From a vaccine produced by Pfizer and BioNTech.

Why did Britain allow the vaccine before the United States?

Countries test vaccines differently. Instead of accepting the findings of vaccine makers as regulators in Britain and elsewhere in Europe, US regulators have reanalyzed the initial data from trials to validate the results.

To speed up the process, Britain’s Medicines and Healthcare Products Regulatory Agency asked its experts to review vaccine data as soon as it became available, and separate teams worked in parallel on different parts of the process, rather than waiting for another team to finish. But the question of whether it acted in a hurry, or whether the United States is wasting valuable time nonetheless sparked an enthusiastic debate among scientists and industry experts on Wednesday.

What about the rest of Europe?

Britain came out of the European Union’s regulatory orbit to approve a vaccine early, due to the emergency powers that the bloc gives countries in the event of a pandemic. Once Britain ends its separation from the European Union on December 31, those powers to approve vaccines on their own will become permanent.

Other countries in the European Union are waiting for the European Union’s regulatory body, the European Medicines Agency, to issue a vaccine, which will not happen before December 29.

Does licensing in Britain affect the supply of the vaccine to other countries?

Pfizer executives said on Wednesday that they had already heard from other countries, in light of Britain’s approval, looking to speed up its approval process.

British rule has offered little relief to poor countries that cannot buy supplies up front and may struggle to pay for vaccines and the extraordinary demands to distribute them.


Thank you for joining me for today’s briefing. See you next time.

– Natasha


Thank you so much
To Theodore Kim and Sean Singh to stop the news. You can reach Natasha and the team at briefing@nytimes.com.

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